Moisture Barrier Coating Systems

Care Pharma chem has developed products for excellent moisture barrier coating for moisture sensitive drugs. Cotab MFC provide good stability and protection for hygroscopic drugs.

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Overview

Care Pharma Chem’s Moisture Barrier Coating Systems are engineered to protect hygroscopic and moisture-sensitive formulations by reducing water vapor transmission and enhancing stability performance.

These systems combine optimized polymer blends to deliver controlled film formation, mechanical strength and improved storage protection across conventional coating processes. Available in both solvent-based and aqueous systems, our moisture barrier coatings are designed for consistent application and defined weight gain control.

Available Grades & Technical Specifications

Specialized coating systems for moisture protection and stability enhancement.

GradePolymer BaseReconstitution LevelRecommended Weight Gain
Cotab MFC (Solvent-Based Barrier)HPMC + Ethyl Cellulose5% in organic solvent (IPA 40% + MDC 60%)2.5 – 3.5%
Cotab AFC P+ (Aqueous Barrier Use)PVA + Lecithin15 – 20% (Aqueous)2.5 – 3.0%

Key Performance Benefits

01

Moisture Protection

Reduces water vapor transmission rates effectively.

02

Stability Enhancement

Improves shelf-life performance of sensitive APIs.

03

Film Integrity

Provides mechanical strength and flexibility to the coating.

04

Process Compatibility

Suitable for standard and automated coating equipment.

Application & Stability Considerations

  • Controlled suspension preparation and de-aeration
  • Uniform spray application for consistent film thickness
  • Optimized drying parameters to prevent moisture entrapment
  • Defined weight gain monitoring for barrier efficacy
  • Stability validation under ICH guidelines (Accelerated & Real-time)
  • Packaging compatibility assessment

Barrier Performance Characteristics

Moisture barrier systems are formulated to reduce water vapor transmission while maintaining coating flexibility and process efficiency. Performance evaluation should be conducted under defined environmental conditions to verify stability improvements and shelf-life extension.

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